Sexuality Among Young Danes Treated for Long-Lasting or Severe Physical Disease: Baseline Findings in a Nationwide Cohort Study.

PURPOSE: Sexual ramifications of physical disease are well-documented in adult populations, but are scarcely investigated among adolescents and young adults (AYA). This study compared measures of sexuality and sexual health among 8,696 15-year-old to 24-year-old Danes with and without a history of treatment for long-lasting or severe physical disease. METHODS: Using baseline data from Project SEXUS, a nationally representative cohort study on sexual health in the Danish population, differences in various domains of sexual behaviors and sexual health between AYA who have and AYA who have not been treated for long-lasting or severe physical disease were investigated. Logistic regression analyses yielded demographically weighted age-adjusted odds ratios (ORs) for associations between physical diseases and sexual outcomes. RESULTS: AYA treated for long-lasting or severe physical disease resembled their healthy peers on fundamental aspects of sexual interest, activity and satisfaction. However, significantly increased odds ratios of various sexual difficulties and dysfunctions, early sexual debut, high sex partner numbers, discontentment with body or genital appearance, gender nonconformity, nonheterosexuality, and exposure to sexual assaults were observed, overall or within specific disease categories. DISCUSSION: The overall similarity in sexual profiles between AYA treated for physical disease and healthy peers indicates that clinicians should routinely address questions related to sexuality and relationships when encountering AYA with chronic health conditions. Moreover, the observed excess of certain adversities, including sexual assaults, among physically ill AYA highlights the need for preventive measures and counseling services specifically targeted at AYA afflicted by physical disease.

Conocimiento y conductas sexuales de las mujeres gestantes / Knowledge and sexual behaviors of pregnant women / Conhecimento e comportamentos sexuais de mulheres grávidas

Introducción: escasos son los estudios que investigan el conocimiento sexual y las conductas sexuales de las mujeres dentro de un periodo tan importante como lo es el embarazo. En esta etapa se producen una serie de cambios que repercuten en su vida y por lo tanto en su sexualidad, por tal motivo es que surge realizar este trabajo de investigación. Objetivo: evaluar el nivel de conocimiento y conducta sexual durante la gestación, en un grupo de gestantes que acuden al Centro de Atención Periférica Número 8 perteneciente a la Dirección General de Atención Periférica de la Dirección Nacional de Sanidad de la Fuerzas Armadas. Materiales y métodos: se realizó un análisis observacional, descriptivo y prospectivo de cohorte transversal de los datos obtenidos a través de entrevistas realizadas a embarazadas. Se entrevistan gestantes que cursan los tres trimestres de embarazo y concurren a sus controles obstétricos en el periodo comprendido entre el 22 de abril y 22 de julio de 2021 que cumplen con los criterios de inclusión y exclusión. Para alcanzar el objetivo se aplicó un cuestionario con respuestas cerradas que consta de 11 preguntas basadas en conocimientos y conductas sexuales en gestantes. Resultados: el 52% de nuestras pacientes gestantes encuestadas tienen más de 30 años, 52% cursa su primera gestación y 51% un embarazo no deseado, pero si aceptado. El 61% de ellas dicen que el estar embarazadas afectó su actividad sexual, 39% refiere que son más satisfactorias las relaciones sexuales en el segundo trimestre, 78% manifiesta que el mantener relaciones sexuales no adelanta el parto, el 83% expresa que la posición menos recomendada es boca arriba, el 9% no saben dónde se localiza el tapón mucoso y el 100% de las encuestadas no tuvo educación sobre sexualidad en los controles prenatales. Conclusiones: durante el embarazo se producen cambios anatómicos, psicológicos y emocionales que provocan cambios en la actividad sexual. La educación que tienen sobre sexualidad es nula por lo que es recomendable la implementación de programas formativos de educación sexual en gestantes y sus parejas para afrontar una salud sexual plena.

Introduction: there are few studies that investigate the sexual knowledge and sexual behaviors of women in such an important period as pregnancy. During this stage, a series of changes take place that have repercussions in their lives and therefore in their sexuality, which is the reason why this research work has been carried out. Objective: to evaluate the level of knowledge and sexual behavior during pregnancy in a group of pregnant women attending the Peripheral Care Center Number 8 belonging to the General Directorate of Peripheral Care of the National Health Directorate of the Armed Forces. Materials and methods: an observational, descriptive and prospective cross-sectional cohort analysis of the data obtained through interviews with pregnant women was carried out. Pregnant women in the three trimesters of pregnancy and attending their obstetric check-ups between April 22 and July 22, 2021 who met the inclusion and exclusion criteria were interviewed. To achieve the objective, a questionnaire with closed answers consisting of 11 questions based on knowledge and sexual behaviors in pregnant women was applied. Results: 52% of our pregnant patients surveyed were over 30 years of age, 52% were in their first pregnancy and 51% had an unwanted pregnancy, but accepted it. 61% of them said that the pregnancy was unwanted. Sixty-one percent of them say that being pregnant affected their sexual activity, 39% say that sexual relations are more satisfactory in the second trimester, 78% say that having sexual relations does not advance labor, 83% say that the least recommended position is on the back, 9% do not know where the mucus plug is located and 100% of the respondents had no education on sexuality in prenatal checkups. Conclusions: During pregnancy there are anatomical, psychological and emotional changes that cause changes in sexual activity. The education they have about sexuality is null, so it is advisable to implement sex education programs for pregnant women and their partners in order to achieve full sexual health.

Introdução: há poucos estudos que investiguem o conhecimento sexual e o comportamento sexual das mulheres durante um período tão importante como a gravidez. Nesta fase, ocorre uma série de mudanças que têm repercussões em suas vidas e, portanto, em sua sexualidade, razão pela qual este estudo de pesquisa foi realizado. Objetivo: avaliar o nível de conhecimento e comportamento sexual durante a gravidez em um grupo de mulheres grávidas que freqüentam o Centro de Atenção Periférica Número 8 pertencente à Direção Geral de Atenção Periférica da Direção Nacional de Saúde das Forças Armadas. Materiais e métodos: foi realizada uma análise observacional, descritiva e prospectiva de coorte transversal dos dados obtidos através de entrevistas com mulheres grávidas. Foram entrevistadas mulheres grávidas no terceiro trimestre de gestação e que compareceram aos check-ups obstétricos entre 22 de abril e 22 de julho de 2021, que preenchiam os critérios de inclusão e exclusão. Para alcançar o objetivo, foi aplicado um questionário com respostas fechadas que consiste em 11 perguntas baseadas em conhecimentos e comportamentos sexuais em mulheres grávidas. Resultados: 52% de nossas pacientes grávidas pesquisadas tinham mais de 30 anos de idade, 52% estavam grávidas pela primeira vez e 51% tiveram uma gravidez indesejada, mas aceitaram-na. 61% deles dizem que estar grávida afetou sua atividade sexual, 39% dizem que as relações sexuais são mais satisfatórias no segundo trimestre, 78% dizem que ter relações sexuais não antecipa o trabalho de parto, 83% dizem que a posição menos recomendada é na parte de trás, 9% não sabem onde o plugue de muco está localizado e 100% dos entrevistados não tiveram nenhuma educação sobre sexualidade nos check-ups pré-natais.

Actitud hacia la vejez como factor predictor de las actitudes hacia la sexualidad del adulto mayor en población mexicana / Attitude towards old age as a predictor of attitudes towards sexuality of the elderly in the Mexican population

Objetivo principal: determinar el efecto de la actitud que presentan los adultos mexicanos respecto a la vejez y a la sexualidad del adulto mayor. Metodología: Estudio correlacional-predictivo y transversal. La muestra incluyó 364 adultos entre 18 y 59 años del Estado de Coahuila de Zaragoza, México. Se aplicaron el cuestionario de actitudes a la vejez y la escala de actitudes hacia la sexualidad del adulto mayor. Los análisis estadísticos incluyeron análisis descriptivos e inferencial. Resultados principales: mayor actitud negativa hacia la vejez, menor actitud favorable hacia la sexualidad en la vejez, además, la actitud de los adultos mexicanos hacia la vejez es un factor predictor que influye negativamente en un 11,8 % sobre las actitudes hacia la sexualidad en la vejez. Conclusión principal: las actitudes hacia la vejez son un factor predictor de la actitud hacia la sexualidad del adulto mayor, es decir son un factor importante para no estigmatizar el proceso de envejecimiento.(AU)

Objective: determine the effect of the attitude towards old age on the attitude towards sexuality of the elderly in Mexican adults. Methods: Correlational-predictive and cross-sectional study. The sample included 364 adults between 18 and 59 years of age from Coahuila State of Zaragoza, Mexico. The scales of attitudes toward older adult sexuality and the questionnaire of attitudes toward old age were applied. Statistical analyzes included descriptive and inferential analyzes. Results: greater negative attitude toward old age, less favorable attitude toward sexuality in old age, besides that attitude toward old age is a predictor that negatively influences attitudes toward sexuality in old age of mexican adults in 11,8 %. Conclusions: attitudes towards old age is a predictor of the attitude towards sexual-ity of the elderly, that is, it is an important factor in not stigmatizing the aging process.(AU)

Função sexual, sintomatologia depressiva e qualidade de vida de pessoas submetidas à terapia hemodialítica / Función sexual, síntomas depresivos y calidad de vida de las personas en tratamiento de hemodiálisis / Sexual function, depressive symptoms and quality of life of people undergoing hemodialysis therapy

RESUMO Objetivo analisar a correlação entre função sexual, sintomatologia depressiva e qualidade de vida de pessoas em tratamento hemodialítico. Método estudo transversal desenvolvido com 54 participantes. A coleta de dados ocorreu entre os meses de março a maio de 2020. Os dados foram analisados com os testes de Mann-Whitney e Correlação de Spearman, com intervalo de confiança de 95%. Resultados a correlação entre a função sexual e a sintomatologia depressiva somente foi clinicamente relevante para as mulheres (ρ= -0,724). Já em relação à qualidade de vida, observou-se que a função sexual geral dos homens está negativamente correlacionada com a dimensão dor (ρ= -0,349) e com a função social (ρ= -0,347). Já para as mulheres, a função sexual geral está positivamente correlacionada com a função física (ρ= 0,501), saúde geral (ρ= 0,737), componente mental (ρ= 0,497), sono (ρ= 0,753), qualidade da interação social (ρ= 0,621) e com a satisfação do paciente (ρ= 0,457). Conclusão e implicações para a prática o aumento da função sexual esteve fortemente correlacionado com a redução de sintomatologia depressiva e com o aumento da qualidade de vida, implicando a necessidade de fortalecer as abordagens sexuais por meio de protocolos que ofereçam fluxos de encaminhamento às equipes transdisciplinares especializadas.

RESUMEN Objetivo analizar la correlación entre función sexual, síntomas depresivos y calidad de vida de personas en hemodiálisis. Método estudio transversal desarrollado con 54 participantes. La recolección de datos ocurrió entre marzo y mayo de 2020. Los datos fueron analizados mediante las pruebas de Mann-Whitney y Correlación de Spearman, con un intervalo de confianza del 95%. Resultados la correlación entre la función sexual y los síntomas depresivos solo fue clínicamente relevante para las mujeres (ρ= -0,724). En cuanto a la calidad de vida, se observó que la función sexual general de los hombres se correlaciona negativamente con la dimensión dolor (ρ= -0,349) y con la función social (ρ= -0,347). Para las mujeres, la función sexual general se correlaciona positivamente con la función física (ρ= 0,501), salud general (ρ= 0,737), componente mental (ρ= 0,497), sueño (ρ= 0,753), calidad de la interacción social (ρ= 0,621) y con la satisfacción del paciente (ρ= 0,457). Conclusión e implicaciones para la práctica el aumento de la función sexual se correlacionó fuertemente con la reducción de los síntomas depresivos y con el aumento de la calidad de vida, lo que implica la necesidad de fortalecer los abordajes sexuales a través de protocolos que ofrezcan flujos de derivación para equipos transdisciplinarios especializados.

Objective to analyze the correlation between sexual function, depressive symptomatology and quality of life of people on hemodialysis treatment. Method a cross-sectional study developed with 54 participants. Data collection occurred between the months of March and May 2020. The data were analyzed with the Mann-Whitney and Spearman Correlation tests, with a 95% confidence interval. Results the correlation between sexual function and depressive symptomatology was only clinically relevant for women (ρ= -0.724). Regarding quality of life, it was observed that the overall sexual function of men is negatively correlated with the pain dimension (ρ= -0.349) and with the social function (ρ= -0.347). For women, overall sexual function is positively correlated with physical function (ρ= 0.501), general health (ρ= 0.737), mental component (ρ= 0.497), sleep (ρ= 0.753), quality of social interaction (ρ= 0.621), and patient satisfaction (ρ= 0.457). Conclusion and implications for the practice increased sexual function was strongly correlated with reduced depressive symptoms and increased quality of life, implying the need to strengthen sexual approaches through protocols that provide referral flows to specialized trans-disciplinary teams.

p16INK4A Expression in Condyloma Acuminata Lesions Associated with High-Risk Human Papillomavirus Infection.

OBJECTIVE: The objective of this study was to discover the possible correlation between p16INK4A expression and the LR/HR-HPV infection in condyloma acuminate (CA) lesions. MATERIALS AND METHOD: This cross-sectional study was conducted during January-December 2017 on 33 CA patients. The expression of p16INK4A was detected by immunohistochemistry (IHC) staining. The positive interpretation was carried out by scoring which score 0 was negative, score 1 was sporadic, score 2 was focal, and score 3 was diffuses. The HPV genotypes were identified by reverse line blot, and 40 genotypes of HPV detected, including HR-HPV (HPVs 16, 18, 26, 31, 33,35, 39, 45, 51, 52, 53, 56, 58, 59, 66, 67, 68a, 68b, 69, 73, and 82) and LR-HPV (HPVs 6, 11, 40, 42, 43, 44, 54, 55, 61, 62, 64, 70, 71, 72, 81, 83, 84, 87, 89, and 90). RESULTS: The expression of p16INK4A was significantly correlated with HR-HPV infection. Patients infected with HR-HPV had 0.644 times higher possibility to express p16INK4A gene compared to those infected with LR-HPV. LR-HPV genotypes detected in CA patients were HPVs 6, 11, 42, 61, 54, 81, 87, 89, and 90 and HR-HPV genotypes were HPVs 18, 26, 45, 51, 52, 67, 68B, 69, and 82. LR-HPV was found in 19/33 of patients and HR-HPV was in 14/33 of patients. The expression of p16INK4A in CA lesions was diffuse in15.2% of patients, was focal in 24.2% of patients , was sporadic in 39.4% of patients were, and was negative in 21.2% of patients . In LR-HPV group, there was no diffuse expression, focal expression was observed in 15.8%, sporadic in 47.4%, and negative in 36.8%, while in HR-HPV group, p16INK4A expression was detected in all lesions , in a way that its expression was diffuse in 35.7%, focal in 35.7%, and sporadic in 28.6%. CONCLUSION: IHC is a routine method in histopathological diagnosis, therefore the detection of p16INK4A expression by IHC can be used as a biomarker for HR-HPV infection diagnosis.

Epidemiological risk factors associated with primary infection by Epstein-Barr virus in HIV-1-positive subjects in the Brazilian Amazon region.

To identify the prevalence and risk factors for primary Epstein-Barr virus (EBV) infection in human immunodeficiency virus (HIV)-1-positive adult treatment-naïve patients between January 2018 and December 2019 in a state of the Brazilian Amazon region. A total of 268 HIV-1 positive patients and 65 blood donors participated in the study. Epidemiological data were obtained from medical records and through a designed questionnaire. EBV infection was screened by the semiquantitative detection of anti-viral capsid antigen (VCA) EBV IgM and IgG, followed by molecular detection of the EBNA-3C gene. The plasma viral loads of HIV-1 and EBV were quantified using a commercial kit. The prevalence of primary coinfection was 7.12%. The associated risk factors were education level, family income, history of illicit drug use and sexually transmitted infections, homosexual contact and condom nonuse. Approximately 58.5% had late initiation of highly active antiretroviral therapy, which influenced the risk of HIV-EBV 1/2 multiple infection (odds ratio (OR): 4.76; 95% CI 1.51-15.04) and symptom development (p = 0.004). HIV viral load was associated with patient age (OR: 2.04; 95% CI 2.01-2.07; p = 0.026) and duration of illicit drug use (OR: 1.57; 95% CI 1.12-2.22; p = 0.0548). EBV viral load was associated with younger age (OR: 0.82; 95% CI 0.79-1.03; p = 0.0579). The replication of both viruses was associated with symptom development (HIV = OR: 2.06; 95% CI 1.22-3.50; p = 0.0073; EBV = OR: 8.81; 95% CI 1-10; p = 0.0447). The prevalence of HIV/EBV coinfection was lower than that observed in other studies, and social vulnerability and promiscuous sexual behavior were associated risk factors. A long time of HIV-1 infection, without therapy, influenced the risk of coinfection and disease progression. The viral loads of both viruses may be associated with some epidemiological aspects of the population.

Epidemiology of anal human papillomavirus infection and high-grade squamous intraepithelial lesions in 29 900 men according to HIV status, sexuality, and age: a collaborative pooled analysis of 64 studies.

BACKGROUND: Robust age-specific estimates of anal human papillomavirus (HPV) and high-grade squamous intraepithelial lesions (HSIL) in men can inform anal cancer prevention efforts. We aimed to evaluate the age-specific prevalence of anal HPV, HSIL, and their combination, in men, stratified by HIV status and sexuality. METHODS: We did a systematic review for studies on anal HPV infection in men and a pooled analysis of individual-level data from eligible studies across four groups: HIV-positive men who have sex with men (MSM), HIV-negative MSM, HIV-positive men who have sex with women (MSW), and HIV-negative MSW. Studies were required to inform on type-specific HPV infection (at least HPV16), detected by use of a PCR-based test from anal swabs, HIV status, sexuality (MSM, including those who have sex with men only or also with women, or MSW), and age. Authors of eligible studies with a sample size of 200 participants or more were invited to share deidentified individual-level data on the above four variables. Authors of studies including 40 or more HIV-positive MSW or 40 or more men from Africa (irrespective of HIV status and sexuality) were also invited to share these data. Pooled estimates of anal high-risk HPV (HR-HPV, including HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68), and HSIL or worse (HSIL+), were compared by use of adjusted prevalence ratios (aPRs) from generalised linear models. FINDINGS: The systematic review identified 93 eligible studies, of which 64 contributed data on 29 900 men to the pooled analysis. Among HIV-negative MSW anal HPV16 prevalence was 1·8% (91 of 5190) and HR-HPV prevalence was 6·9% (345 of 5003); among HIV-positive MSW the prevalences were 8·7% (59 of 682) and 26·9% (179 of 666); among HIV-negative MSM they were 13·7% (1455 of 10 617) and 41·2% (3798 of 9215), and among HIV-positive MSM 28·5% (3819 of 13 411) and 74·3% (8765 of 11 803). In HIV-positive MSM, HPV16 prevalence was 5·6% (two of 36) among those age 15-18 years and 28·8% (141 of 490) among those age 23-24 years (ptrend=0·0091); prevalence was 31·7% (1057 of 3337) among those age 25-34 years and 22·8% (451 of 1979) among those age 55 and older (ptrend<0·0001). HPV16 prevalence in HIV-negative MSM was 6·7% (15 of 223) among those age 15-18 and 13·9% (166 of 1192) among those age 23-24 years (ptrend=0·0076); the prevalence plateaued thereafter (ptrend=0·72). Similar age-specific patterns were observed for HR-HPV. No significant differences for HPV16 or HR-HPV were found by age for either HIV-positive or HIV-negative MSW. HSIL+ detection ranged from 7·5% (12 of 160) to 54·5% (61 of 112) in HIV-positive MSM; after adjustment for heterogeneity, HIV was a significant predictor of HSIL+ (aPR 1·54, 95% CI 1·36-1·73), HPV16-positive HSIL+ (1·66, 1·36-2·03), and HSIL+ in HPV16-positive MSM (1·19, 1·04-1·37). Among HPV16-positive MSM, HSIL+ prevalence increased with age. INTERPRETATION: High anal HPV prevalence among young HIV-positive and HIV-negative MSM highlights the benefits of gender-neutral HPV vaccination before sexual activity over catch-up vaccination. HIV-positive MSM are a priority for anal cancer screening research and initiatives targeting HPV16-positive HSIL+. FUNDING: International Agency for Research on Cancer.

Sexual Orientation and Functional Limitations: Cross-sectional Analyses From the Adult Psychiatric Morbidity Survey.

OBJECTIVE: To assess the association between sexual orientation and functional limitations in a large representative sample of the English population. DESIGN: Cross-sectional. SETTING: Data were from the 2007 Adult Psychiatric Morbidity Survey. PARTICIPANTS: A total of 7403 adults aged 16-95 years (51.4% female; mean age, 46.3±18.6y) were included in the present study. INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Sexual orientation was assessed using 2 items adapted from the Kinsey scale and was dichotomized into heterosexual and sexual minority orientation. Functional limitations were assessed using 7 activities of daily living (ADL) and instrumental activities of daily living (IADL). Functional limitations were defined as at least 1 difficulty in 1 of 7 ADL and IADL. Adjusted logistic regression analyses were conducted to investigate the association between sexual orientation (independent variable) and functional limitations (dependent variable). RESULTS: The level of sexual minority orientation and prevalence of functional limitations in the sample was 7.1% and 32.9%, respectively. After adjusting for several potential confounders, sexual minority orientation was positively and significantly associated with functional limitations (odds ratio, 1.51; 95% confidence interval, 1.18-1.95; reference group: heterosexual orientation). CONCLUSIONS: Based on the findings of this study, interventions aiming to prevent against and/or manage/reduce functional limitations in sexual minorities are needed. More research is also warranted to better understand mediators (eg, obesity, cognitive complaints, psychiatric disorders) involved in the sexual orientation-functional limitation relationship.

Childhood gender nonconformity and the stability of self-reported sexual orientation from adolescence to young adulthood in a birth cohort.

This study quantified changes in self-reported sexual orientation from adolescence to early adulthood, and whether childhood gender nonconformity (GNC) predicted sexual orientation changes. Youth (2,678 boys and 3,359 girls; 96.09% ethnically White) from the Avon Longitudinal Study of Parents and Children (ALSPAC) were included. Self-reported sexual orientation was measured using sexual attraction (5-point scale) at ages 15.5, 21, and 23. GNC was measured via Preschool Activities Inventory at ages 2.5, 3.5, and 4.75 years. The prevalence of boys and girls who reported being gay/lesbian increased from 15.5 to 21 years old whereas the proportion of bisexuals was relatively stable for both sexes. Among boys, heterosexuality and being gay were equally stable and relatively more stable compared to bisexuality. Among girls, reporting being lesbian and bisexual were equally unstable and relatively less stable than heterosexuality. Girls reporting being lesbian were more likely to report changes in their sexual orientation than gay adolescent boys. The stability of being lesbian and bisexual among girls, and bisexuality among boys, increased over time. Overall, few people changed their self-reported sexual orientation between ages 21 and 23. GNC at 2.5 years, and changes in GNC from 2.5 to 4.75 years, predicted being lesbian/gay at 15.5, 21, and 23 years and changes from being heterosexual to lesbian/gay from 15.5 to 21 years in each sex. In conclusion, self-reported sexual orientation from adolescence to young adulthood is relatively stable in males compared to females, and childhood GNC is a predictor of any, albeit small, sexual orientation changes. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Assessment of an onco-sexology support and follow-up program in cervical or vaginal cancer patients undergoing brachytherapy.

PURPOSE: Women's sexual health and wellbeing with cervical or vaginal cancer may be largely affected by complications from external beam radiotherapy (EBRT) and utero-vaginal brachytherapy (BT), of which vaginal stenosis is the main complication. The objective of this study was to assess the impact of support by a nurse sexologist on sexuality, vaginal side-effects, and the quality of clinical follow-up in patients treated with brachytherapy for cervical or vaginal cancer. METHODS: We performed a retrospective study of the sexuality of women treated for cervical or vaginal cancer. Data from patients with cervical or vaginal cancer who underwent brachytherapy between 2013 and 2017 were collected at Institut Universitaire de Cancer de Toulouse-Oncopôle (IUCT-Oncopôle). Patients were divided into two groups: group A (intervention group) received support from a nurse sexologist and group B (control group) did not. The chi-square test and a logistic multivariate model were used for data analysis. RESULTS: A total of 156 patients were included in this study, including 57.7% who were followed by a nurse sexologist. We observed low compliance in using vaginal dilators after brachytherapy and/or radiotherapy over time regardless of the group, and patients' sexual activity was inadequately addressed. Information regarding the resumption of sexuality 2 months after treatment was missing in 1.1% of patients in group A and in 36.4% of patients in group B. Multivariate analysis showed that patients in group A had a lower risk of developing vaginal stenosis with OR crude = 0.5 (95% CI = 0.25-0.92) and OR adj. = 0.5 (95% CI = 0.26-1.09) compared with those in group B. CONCLUSION: This retrospective study highlights the lack of information collected by physicians during follow-up concerning the sexuality of patients with cervical or vaginal cancer treated by EBRT and BT. The support offered by nurse sexologists in improving patients' sexual activity and reducing their physical side-effects such as vaginal stenosis is likely to be beneficial. A prospective study is currently being conducted to validate the present findings.

Associations among sexuality-related factors, recent two-week morbidity and annual hospitalization in female migrant workers: a cross-sectional study in southern China.

To explore the influence of sexuality-related factors on recent two-week morbidity and annual hospitalization in female migrant workers, 880 Chinese rural-to-urban female migrant workers aged 16-57 years were studied. Clustered logistic regression analyses revealed that women who never or seldom experienced lubrication difficulties had a lower risk of recent two-week morbidity (adjusted odds ratio [OR] = 0.32, 95% confidence interval [CI] = 0.17-0.60, P< 0.001; adjusted OR = 0.35, 95% CI = 0.18-0.69, P= 0.003) than those who always experienced lubrication difficulties; women who never felt a lack of sexual interest had a significantly lower risk of annual hospitalization (adjusted OR = 0.40, 95% CI = 0.20-0.79, P= 0.009) than those who always or seldom lacked sexual interest, and women who never felt sexual satisfaction had a higher risk of annual hospitalization (adjusted OR = 3.08, 95% CI = 1.75-5.42, P< 0.001) than those who always or seldom experienced sexual satisfaction. The independent contributions of sexuality-related factors to the risk of recent two-week morbidity and annual hospitalization were 5.8% and 29.5%, respectively. This study suggests that sexuality may have a modest influence on recent two-week morbidity and a dominant impact on annual hospitalization.

Sexual minority status, social adversity and risk for psychotic disorders-results from the GROUP study.

BACKGROUND: Lesbian, bisexual, or gay individuals (LBGs) have an increased risk for mental health problems compared to heterosexuals, but this association has sparsely been investigated for psychotic disorders. The aim of this study was: (1) to examine whether LBG sexual orientation is more prevalent in individuals with a non-affective psychotic disorder (NAPD) than in people without a psychotic disorder; and if so, (2) to explore possible mediating pathways. METHODS: Sexual orientation was assessed in the 6-year follow-up assessment of the Dutch Genetic Risk and Outcome of Psychosis study (GROUP), a case-control study with 1547 participants (582 patients with psychotic disorder, 604 siblings, and 361 controls). Binary logistic regression analyses were used to calculate the risk of patients with a psychotic disorder being LBG, compared to siblings and controls. Perceived discrimination, history of bullying, childhood trauma (CT), and sexual identity disclosure were investigated as potential mediating variables. RESULTS: The proportion of individuals with LBG orientation was 6.8% in patients (n = 40), 4.3% in siblings (n = 26), and 2.5% in controls (n = 10). The age- and gender-adjusted odds ratio of LBG for patients was 1.57 (95% CI 1.08-2.27; p = 0.019), compared to siblings and controls. Discrimination, bullying, and CT all partially mediated this association. CONCLUSIONS: Adverse social experiences related to sexual minority status may increase the risk for NAPD. Sexual identity, behavior, and difficulties need more attention in everyday clinical practice.

Relationship between sexual orientation and psychotic experiences in the general population in England.

BACKGROUND: Non-heterosexual individuals are at high risk for a variety of factors associated with the emergence of psychotic experiences (PEs) (e.g. common mental disorders, substance use, and stress). However, there is a scarcity of data on the association between sexual orientation and PEs. Therefore, the aim of this study was to examine the sexual orientation-PE relationship, and to identify potential mediators in this relationship. METHODS: This study used nationally representative cross-sectional data from the 2007 Adult Psychiatric Morbidity Survey. Sexual orientation was dichotomized into heterosexual and non-heterosexual. Past 12-month PE was assessed with the Psychosis Screening Questionnaire. Regression and mediation analyses were conducted to analyze the association between sexual orientation and PEs, and to identify potential mediators involved in this relationship. RESULTS: The final sample consisted of 7275 individuals aged ⩾16 years. The prevalence of non-heterosexual orientation and any PE was 7.1% and 5.5%, respectively. After adjusting for sex, age, and ethnicity, non-heterosexual orientation was positively associated with any PE (odds ratio 1.99, 95% confidence interval 1.34-2.93). The strongest mediators involved in this relationship were borderline personality disorder (BPD) traits (mediated percentage = 33.5%), loneliness (29.1%), and stressful life events (25.4%). CONCLUSIONS: These findings suggest that there is a positive relationship between sexual orientation and PEs in the general population in England, and that underlying mechanisms may involve BPD traits, loneliness, and stressful life events. Future studies with a longitudinal design are warranted to shed more light on how these factors are implicated in the association between sexual orientation and PEs.

Sexualidade de idosos participantes de um centro de convivência / Sexuality of elderly people participating in a cohabitation center / Sexualidad de las personas mayores que participan en un centro comunitario

Objetivo: analisar o comportamento sexual de idosos participantes de um centro de convivência. Método: estudo transversal, realizado com 91 idosos participantes de um centro de convivências em Tangará da Serra, Mato Grosso. A amostra foi de conveniência. A coleta de dados foi realizada em 2016, por meio de entrevista utilizando questionário estruturado. A análise foi descritiva. Resultados: 45,1%dos idosos têm vida sexual ativa, 95,1% têm desejo pelas práticas sexuais e 94,5% não faz uso de medidas preventivas para infecções sexualmente transmissíveis. A maioria referiu dificuldades no ato sexual (82,9%) sendo as mais prevalentes o ressecamento vaginal(29,4%), ejaculação precoce(17,6%) e problemas na ereção (11,8%). A maioria dos idosos citou conhecer as seguintes IST: HIV/AIDS (67%), gonorreia (41,8%), papiloma vírus humano (HPV) (27,5%) e sífilis (22,0%). Conclusão: Os idosos apresentam dificuldades no ato sexual, não usam preservativos, porém, têm desejo sexual. Há necessidade de implementar intervenções para promoção da saúde sexual na velhice

Objective: to analyze the sexual behavior of elderly people participating in a community center. Method: cross-sectional study, carried out with 91 elderly people participating in a community center in Tangará da Serra, Mato Grosso. The sample was of convenience. Data collection was carried out in 2016, through an interview using a structured questionnaire. The analysis was descriptive. Results: 45.1% of the elderly have an active sex life, 95.1% have a desire for sexual practices and 94.5% do not use preventive measures for sexually transmitted infections. Most reported difficulties in the sexual act (82.9%), the most prevalent being vaginal dryness (29.4%), premature ejaculation (17.6%) and problems with erection (11.8%). Most elderly people mentioned knowing the following STIs: HIV / AIDS (67%), gonorrhea (41.8%), human papilloma virus (HPV) (27.5%) and syphilis (22.0%). Conclusion: The elderly have difficulties in the sexual act, do not use condoms, however, they have sexual desire. There is a need to implement interventions to promote sexual health in old age

Objetivo: analizar el comportamiento sexual de personas mayores que participan en un centro comunitario. Método: estudio transversal, realizado con 91 adultos mayores en un centro comunitario de Tangará da Serra, Mato Grosso. La muestra fue de conveniencia. La recolección de datos se llevó a cabo en 2016, a través de una entrevista mediante un cuestionario estructurado. El análisis fue descriptivo. Resultados: el 45,1% de los adultos mayores tiene una vida sexual activa, el 95,1% tiene deseo de prácticas sexuales y el 94,5% no utiliza medidas preventivas para las infecciones de transmisión sexual. La mayoría refirió dificultades en el acto sexual (82,9%), siendo las más prevalentes la sequedad vaginal (29,4%), la eyaculación precoz (17,6%) y los problemas de erección (11,8%). La mayoría de los ancianos mencionó conocer las siguientes ITS: VIH / SIDA (67%), gonorrea (41,8%), virus del papiloma humano (VPH) (27,5%) y sífilis (22,0%). Conclusión: Los ancianos tienen dificultades en el acto sexual, no usan condón, sin embargo, tienen deseo sexual. Es necesario implementar intervenciones para promover la salud sexual en la vejez

Female sexuality at reproductive age as an indicator of satisfaction with life - descriptive cross-sectional survey.

INTRODUCTION: Life satisfaction is the result of valuing one's own life, and it is higher when the individual situation is closer to the general norm. It is characterized by dynamic and subjectivity and the way it is perceived is regulated by internal and external factors. Life satisfaction can be described in subjective and objective categories, by various indicators. OBJECTIVE: The aim of the study was to evaluate the determinants of satisfaction with life in selected aspects among women of reproductive age. MATERIAL AND METHODS: The study was conducted on 280 women, selected according to the following criteria: age range 18-45, at least one sexual intercourse per month, lack of chronic diseases or cancer, and consent to participate in the research. The research instruments used were: Satisfaction With Life Scale (SWLS), Sexual Satisfaction Questionnaire (SSQ), Female Sexual Function Index (FSFI). RESULTS: Life satisfaction increased with age (p<0.0001), higher life satisfaction was reported by women with higher education (p<0.001), married, (p<0.01), talked with their partner about their sexual expectations (p=0.03) and did not want to change anything in their sexual life (p<0.001). Analysis revealed a positive correlation between life satisfaction and sexual satisfaction (p < 0.0001). CONCLUSIONS: Higher level of sexual satisfaction and sexual health is related to better satisfaction with life. Factors affecting sexual satisfaction include residence, having children, discussing one's sexual expectations with their partner, feeling no need to change one's sex life, and frequency of sexual activity.

Sexual Orientation, Adverse Childhood Experiences, and Comorbid DSM-5 Substance Use and Mental Health Disorders.

OBJECTIVE: To assess the relationships between adverse childhood experiences (ACEs) and comorbid Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5) substance use and mental health disorders across 5 sexual orientation subgroups: lesbian/gay, bisexual, unsure, discordant heterosexual (ie, heterosexual-identified with same-sex attraction or behavior), and concordant heterosexual. METHODS: Data were from the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions-III, a cross-sectional, nationally representative survey of non-institutionalized US adults. Data were collected in households via structured diagnostic face-to-face interviews; the overall response rate was 60.1%. The sample included 36,309 US adults aged 18 years and older. RESULTS: Sexual minorities (gay, lesbian, bisexual), especially bisexual women, reported the highest prevalence of ACEs and comorbid substance use and mental health disorders. Approximately 43.8% of bisexual women reported 4 or more ACEs, and 38.0% of bisexual women reported comorbid substance use and mental health disorders. Multivariable regression analyses indicated a curvilinear relationship between ACEs and comorbid substance use and mental health disorders, and sexual minorities consistently had a higher ACE mean than concordant heterosexual respondents. The majority of sexual minorities with high levels of ACEs had comorbid substance use and mental health disorders. CONCLUSIONS: Sexual minorities are exposed to more ACEs than their heterosexual counterparts in the US. We found evidence that US sexual minorities are at higher risk of comorbid substance use and mental health disorders. These findings reinforce the importance of identifying exposure to ACEs and developing trauma-informed interventions to treat comorbidities in those exposed to multiple ACEs, especially sexual minorities.​.

Interpretación de los cambios en el comportamiento sexual de la mujer durante el embarazo / Interpretation of changes in a woman's sexual behavior during pregnancy

La sexualidad de la mujer durante el embarazo puede presentar notables cambios que muchas veces conllevan a que las relaciones sexuales no sean placenteras, con efectos negativos sobre la sexualidad en esta etapa, conduciendo a modificaciones en el patrón de comportamiento sexual de la mujer en esta etapa, en donde casi siempre se produce disminución del coito vaginal y de otras prácticas sexuales de manera injustificada. Se investigó el estado del arte sobre los cambios más importantes que afectan el comportamiento sexual de la mujer embarazada, a partir de la recolección y análisis de diferentes fuentes bibliográficas existentes, para así comprender a interpretar los más importantes cambios sexuales en el embarazo y como estos repercuten en la sexualidad. Se concluyó que en la mayoría de los casos existe menos actividad sexual debido a disminución del deseo sexual, con alteraciones en las fases de la respuesta sexual femenina y que estas situaciones se ven influenciadas por factores externos como socio culturales. Por otro lado se observó que también puede existir efecto positivo sobre la sexualidad durante el embarazo, sobre todo en las mujeres con buenas prácticas sexuales previas a la gestación. OBJETIVOS: Realizar una investigación reflexiva sobre los cambios en el comportamiento sexual de las mujeres durante el embarazo, interpretarlos y determinar sus repercusiones en la vida sexual de las gestantes. CONFIGURACIÓN Y DISEÑO: Cualitativo, estado del arte. MATERIALES Y MÉTODOS: Se trabajó bajo el paradigma interpretativo, mediante la revisión de varios estudios realizados sobre el tema, pudiendo así construir un estado del arte sobre estos cambios sexuales en las gestantes. Se presentan los resultados obtenidos a partir de una recolección y análisis de la bibliografía existente, que se llevó a cabo consultando en bases de datos académicas especializadas en ciencias médicas, lo que permitió la revisión de múltiples artículos científicos, trabajos de investigación, textos académicos y tesis doctorales. RESULTADOS: Durante la gestación tienen lugar una seria de cambios físicos y hormonales que modifican de forma especial la respuesta sexual. Como menciona García (2016), ocurren cambios en la fase de deseo, el cual puede ser bajo en el primer trimestre, para aumentar en el segundo trimestre del embarazo; la fase excitación se ve modificada por la vasocongestión propia del embarazo, por lo que está para algunas mujeres puede verse acompañada de irritación o dolor (Escudero, 2015), pero para otras mujeres no se ve afectada. Manueres y Alvarado (2017), encontraron que algunas gestantes pueden experimentar disconfort o dolor durante el coito y aun así seguir consintiendo a su pareja, lo que podría condicionar desarmonía entre ellos; también evidencian que más de la mitad de las gestantes de su estudio consideran "regular" su vida sexual. Con respecto a la satisfacción sexual, García (2016), evidenció que fue menor a medida que avanza la gestación, en aquellas mujeres que referían un nivel de satisfacción sexual "muy bueno" en el primer trimestre este disminuyo a "bueno" en el segundo y su a vez a "regular" en el tercer trimestre del embarazo como lo muestra el estudio de Sapién y Cordoba (2011), evidenciando que algunos van reduciendo la actividad sexual caracterizada por el coito vaginal a medida que avanza la gestación y en algunos casos la eliminan desde el diagnostico medico de embarazo, lo mismo sucedió con las prácticas de masturbación, felación, sexo oral mutuo, cunnilingus y penetración anal. En otras ocasiones los hombres se implicaron en relaciones sexuales extra maritales. CONCLUSIONES: La mayoría de los autores coinciden en que la actividad sexual, el deseo, la satisfacción y la frecuencia coital y orgásmica presentan una disminución progresiva a lo largo del embarazo en comparación con el estado pre gestacional, estos cambios también parecen estar influenciados por la sexualidad previa al embarazo, de manera que las mujeres que han mostrado buena sexualidad previa al embarazo, la siguen manteniendo en esta etapa

A woman's sexuality during pregnancy can have remarkable changes that often lead to non-pleasurable sex, with negative effects on sexuality at this stage, leading to changes in the pattern of sexual behavior of women at this stage, where there is almost always decreased vaginal intercourse and other sexual practices unjustifiably. State of the art was investigated on the most important changes affecting the sexual behavior of pregnant women, from the collection and analysis of different existing bibliographic sources, in order to understand and interpret the most important sexual changes in pregnancy and how these affect sexuality. It was concluded that in most cases there is less sexual activity due to decreased sexual desire, with alterations in the phases of female sexual response and that these situations are influenced by external factors as socio-cultural. On the other hand, it was observed that there may also be a positive effect on sexuality during pregnancy, especially in woman with good pre-gestacional sexual practices. AIMS: Conduct thoughtful research on changes in women's sexual behavior during pregnancy, interpret them and determine their impact on pregnant women's sex lives. SETTINGS AND DESIGN: Qualitative, state of art. METHODS AND MATERIAL: Work is carried out under the interpretive paradigm, by reviewing several studies carried out on the subject, thus being able to build a state of art on these sexual changes in pregnant women. The results obtained from a collection and analysis of the existing literature, which was carried out by consulting in academic databases specializing in medical sciences, which allowed the review of multiple scientific articles, research papers, academic texts and doctoral theses. RESULTS: During pregnancy, a serious number of physical and hormonal changes take place that significantly modify the sexual response. As García mentions (2016), changes occur in the phase of desire, which may be low in the first trimester, to increase in the second trimester of pregnancy; the excitation phase is modified by the vasocongestion of pregnancy, so it is for some women may be accompanied by irritation or pain (Escudero, 2015), but for other women it is not affected. Manueres and Alvarado (2017), found that some pregnant women may experience disconfort or pain during intercourse and still continue to consent to their partner, which could condition desarmony between them; they also show that more than half of the pregnant women in their study consider their sex life "regulating." With regard to sexual satisfaction, Garcia (2016) showed that it was lower as gestation progressed, in those women who referred to a "very good" level of sexual satisfaction in the first trimester this decreased to "good" in the second and its instead to "regular" in the third trimester of pregnancy as the study of Sapien and Cordoba (2011) shows, showing that some are reducing the sexual activity characterized by vaginal intercourse as gestation progresses and in some cases eliminated it since the medical diagnosis of pregnancy, the same thing happened with masturbation, fellatio, mutual oral sex, cunnilingus and anal penetration. At other times men were involved in extra-marital sex. CONCLUSIONS: Most authors agree that sexual activity, desire, satisfaction, and coital and orgasmic frequency have a progressive decrease throughout pregnancy compared to pre-gestational status, these changes also appear to be influenced by pre-pregnancy sexuality, so that women who have shown good pre-pregnancy sexuality continue to maintain it at this stage

Preferences in Information Processing, Marginalized Identity, and Non-Monogamy: Understanding Factors in Suicide-Related Behavior among Members of the Alternative Sexuality Community.

Suicide-related behavior (SRB) is a mental health disparity experienced by the alternative sexuality community. We assessed mental health, relationship orientation, marginalized identities (i.e., sexual orientation minority, gender minority, racial minority, ethnic minority, and lower education), and preferences in information processing (PIP) as factors differentiating lifetime SRB groups. An online cross-sectional survey study was conducted in 2018. Members of the National Coalition for Sexual Freedom (NCSF; n = 334) took part. Bivariate analyses identified the following SRB risk factors: female and transgender/gender non-binary identity, sexual orientation minority identity, lower education, suicide attempt/death exposure, Need for Affect (NFA) Avoidance, depression, and anxiety. Monogamous relationship orientation was a protective factor. Multi-nomial regression revealed the following: (1) monogamous relationship orientation was a protective factor for suicidal ideation and attempt; (2) lower education was a risk factor for suicide attempt; (3) anxiety was a risk factor for suicide attempt; and (4) depression was a risk factor for suicidal ideation. A two-way interaction showed that elevated NFA Approach buffered the negative impacts of depression. Relationship orientation, several marginalized identities (i.e., based on gender, sexual orientation, and educational level), and PIP all contributed uniquely to SRB. Further study is necessary to understand the role of relationship orientation with suicide. Health education and suicide prevention efforts with NCSF should be tailored to account for marginalized identity, mental health, and NFA factors.

Asociación sexual entre personas que viven con el VIH: manejo de las diferencias serológicas / Sexual partnership between people living with HIV: managing serological diferences / Parceria sexual entre pessoas vivendo com HIV: gerenciando as diferenças sorológicas

OBJETIVO: Analizar si existen diferencias entre las características sociodemográficas, clínicas y afectivas sexuales en las diferentes asociaciones sexuales entre personas viviendo con VIH / sida. MÉTODOS: Se trata de un estudio transversal realizado en un servicio de asistencia especializada en el tratamiento de personas con el Virus de la Inmunodeficiencia Humana, con 173 participantes. Los datos fueron recolectados por medio de entrevistas con cuestionarios construidos para el estudio. RESULTADOS: Se verificaron evidencias estadísticas entre la serología del compañero y el sexo, estado civil, hijo, número de hijos. La serología del compañero sexual también presentó evidencias científicas entre las variables tipo de asociación, uso del preservativo masculino, práctica sexual vaginal insertiva, divulgación del diagnóstico del VIH para la asociación sexual y considera importante la divulgación del VIH para el socio. CONCLUSIÓN: La serología del compañero fue influenciada por las variables sociodemográficas y afectivo-sexuales

OBJECTIVE: To analyze whether there are differences between socio-demographic, clinical and affective-sexual characteristics in the different sexual partnerships between people living with HIV/AIDS. METHODS: This is a cross-sectional study carried out in a care service specialized in the treatment of people with Human Immunodeficiency Virus, with 173 participants. Data were collected through interviews with a questionnaire built for the study. RESULTS: Statistical evidences were verified between the serology of the partner and the sex, marital status, child, number of children. The serology of the sexual partner also presented scientific evidence among the type variables of partnership, use of the male condom, insertive vaginal sex, dissemination of the HIV diagnosis to the sexual partnership and the importance of spreading HIV to the partner. CONCLUSION: The serology of the partner was influenced by sociodemographic and affective-sexual variables

OBJETIVO: Analisar se existe diferenças entres as características sociodemográficos, clínicos e afetivos-sexuais nas diferentes parcerias sexuais entre pessoas vivendo com HIV/aids. MÉTODOS: Trata-se de um estudo transversal realizado em um serviço de assistência especializada no tratamento de pessoas com o Vírus da Imunodeficiência Humana, com 173 participantes. Os dados foram coletados por meio de entrevistas com questionário construído para o estudo. RESULTADO: Verificou-se evidencias estatísticas entre a sorologia do parceiro e o sexo, estado civil, filho, número de filhos. A sorologia do parceiro sexual também apresentou evidências científicas entre as variáveis tipo de parceria, uso do preservativo masculino, prática sexual vaginal insertivo, divulgação do diagnóstico do HIV para a parceria sexual e considera importante a divulgação do HIV para o parceiro. CONCLUSÃO: A sorologia do parceiro foi influenciada pelas variáveis sociodemográficas e afetivo-sexuais

Bullying and Peer Victimization of Minority Youth: Intersections of Sexual Identity and Race/Ethnicity.

BACKGROUND: Youth with multiple minority identities, such as those who are both sexual minority (eg, lesbian, gay, bisexual) and racial/ethnic minority (eg, Black, Latino) may be at increased risk for bullying and peer victimization. METHODS: Youth Risk Behavior Surveillance data (2011-2017) were analyzed (N = 114,881; 50.8% girls; mean age = 15.7 years, SD = 0.03). We used chi-square tests and sex-stratified multiple linear regression models to examine sexual identity and racial/ethnic differences and the intersection between sexual identity and race/ethnicity across 3 forms of bullying and peer victimization, co-occurrence of traditional and electronic bullying, and any type of bullying or peer victimization. RESULTS: Sexual minority youth reported higher odds of bullying and peer victimization than heterosexual youth. White youth reported higher odds of bullying than racial/ethnic minority youth. In intersectional analyses, all sexual minority and racial/ethnic minority boys, and bisexual racial/ethnic minority girls were at higher risk for bullying and peer victimization compared to heterosexual peers of the same race/ethnicity. CONCLUSIONS: This study of a large diverse sample of youth advances our understanding of vulnerability to bullying and peer victimization among youth with multiple minority identities. This research can inform policy initiatives and interventions to prevent peer victimization of vulnerable youth.